[HTML][HTML] Surfactant lung delivery with LISA and InSurE in adult rabbits with respiratory distress

F Ricci, I Bresesti, PAM LaVerde, F Salomone… - Pediatric …, 2021 - nature.com
… for exogenous surfactant administration while reducing lung injury … adult rabbit model of
RDS to evaluate the acute effects of … The pressure recorded at each insufflation volume was …

[HTML][HTML] Small molecule inhibitor adjuvant surfactant therapy attenuates ventilator-and hyperoxia-induced lung injury in preterm rabbits

P Das, T Curstedt, B Agarwal, VM Prahaladan… - Frontiers in …, 2020 - frontiersin.org
… standardized pressures was performed to evaluate the effect … sequence of peak insufflation
pressures and an inspiration: … To assess if CS could decrease opening airway pressure in the …

Corticosteroids in acute lung injury: the dilemma continues

D Mokra, P Mikolka, P Kosutova, J Mokry - International journal of …, 2019 - mdpi.com
… and dilution of pulmonary surfactant. Interstitial and intra-alveolar … using high tidal volumes
and/or high insufflation pressures [2]… In a rabbit model of iv endotoxin-induced lung injury, it …

A systematic review of the influence of continuous positive airway pressure on fetal and newborn animal models: suggestions to improve neonatal respiratory care

AG Gie, TR Hubble, Y Regin, T Salaets, M Zamora… - Neonatology, 2021 - karger.com
… , preterm rabbits, and term mice, have examined the effect of … The effect of CPAP on
endogenous pulmonary surfactant … as an alternative ventilation strategy to limit acute lung injury

[PDF][PDF] An overview of acute lung injury in general and in particular viral infections with specific reference to nebulized surfactant and anticoagulation

J Smith, JМ Zyl - Am. Rev. Respir. Dis, 2020 - researchgate.net
pressure rather than positive pressure insufflation [76]. … direct effect of sPLA2 on the catabolism
of pulmonary surfactant. … and lung compliance in the rabbits, more so in rabbits supported …

[HTML][HTML] Airway closure and expiratory flow limitation in acute respiratory distress syndrome

C Guérin, M Cour, L Argaud - Frontiers in physiology, 2022 - frontiersin.org
… to ventilator-induced lung injury and has decreased over time … to exhale 63% of the insufflated
volume. Right: Corresponding … In rabbits, small airways closure occurred more frequently …

[HTML][HTML] Efficacy, dose–response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs

FJ Walther, AJ Waring, M Otieno, RM DiBlasi - Respiratory Research, 2022 - Springer
lung injury and chronic lung disease. Although noninvasive … Figure 1 demonstrates the
effects of surfactant treatment on … measured 2 h after intratracheal insufflation of dry powder. A …

Pulmonary Surfactant: A Mighty Thin Film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
… to inflate their lungs, leading to severe lung dysfunction. … rabbit pup model which demonstrated
that instillation of natural … may cause lung injury and inflammation beyond surfactant

Asymmetrical lung injury: management and outcome

L Bastia, H Rozé, LJ Brochard - … Respiratory and Critical Care …, 2022 - thieme-connect.com
… in combination with continuous positive airway pressure (CPAP) has … [24] [25] Experimentally,
tracheal gas insufflation (TGI) has … the bedside may have clinical implications on ventilator

Lung and chest wall mechanics in patients with acute respiratory distress syndrome, expiratory flow limitation, and airway closure

C Guérin, N Terzi, LM Galerneau… - Journal of Applied …, 2020 - journals.physiology.org
… ), where Ppeak is the maximal pressure during insufflation. … In rabbits with acute lung injury,
AC occurs in both proximal and … The role of ventilation-induced surfactant dysfunction and …